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June 3, 2026Annals of Internal Medicine0 citations

In adults with acute VTE, apixaban vs. rivaroxaban reduced clinically relevant bleeding at 3 mo

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SMSiraj MithoowaniWLWendy Lim

Key Points

  • This study aims to compare the efficacy of apixaban and rivaroxaban in reducing clinically relevant bleeding in adults with acute venous thromboembolism (VTE).
  • Randomized trial design
  • Participants were adults diagnosed with acute VTE
  • Comparison of clinical bleeding rates at 3 months between apixaban and rivaroxaban
  • The incidence of clinically relevant bleeding was lower in the apixaban group compared to the rivaroxaban group (specific rates not provided).
  • No significant difference in VTE recurrence was noted between treatment groups.
  • Apixaban showed a better safety profile regarding bleeding complications compared to rivaroxaban.
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Cite This Study

Mithoowani et al. (2026) studied this question.

synapsesocial.com/papers/6a1fcb18dee9eb8c0dce8809https://doi.org/10.7326/annals-26-01793-jc
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