Key result
Increasing hemodialysis sessions during pregnancy was associated with a significantly higher live birth frequency (67.2% vs 3.4%, p<0.001) and a lower abortion rate (22.4% vs 79.3%, p<0.001).
Why the study?
The study aimed to investigate pregnancy frequency and evaluate factors affecting live births in hemodialysis patients.
Does increasing the number of hemodialysis sessions improve live birth rates and reduce abortions in pregnant hemodialysis patients?
Cohort (n=145)
Yes
Does increasing the number of hemodialysis sessions improve live birth rates and reduce abortions in pregnant hemodialysis patients?
Increasing the number of hemodialysis sessions during pregnancy significantly improves live birth rates and reduces abortion rates in female hemodialysis patients.
Supports intensified hemodialysis consideration in pregnant dialysis patients; leaves open need for randomized confirmation before practice change.
BACKGROUND/AIM: This study aimed to investigate pregnancy frequency and evaluate the factors affecting live births in hemodialysis (HD) patients. MATERIALS AND METHODS: Female HD patients whose pregnancy was retrospectively reported between January 1, 2014, and December 31, 2019. The duration of HD, primary disease, whether the pregnancy resulted in abortion, stillbirth, or live birth, whether the HD duration was prolonged after diagnosing the pregnancy and whether it accompanied preeclampsia were recorded. RESULTS: In this study, we reached 9038 HD female patients? data in the study. A total of 235 pregnancies were detected in 145 patients. The mean age was 35.42 (35 ± 7.4) years. The mean age at first gestation was 30.8 ± 6.5 years. The average birth week was 32 (28 - 36) weeks. 53.8% (no = 78) of the patients had live birth, 51.7% (no = 70) had at least one abortion in the first 20 weeks, and 13.1% (no = 19) had at least one stillbirth after 20 weeks. The rate of patients' increased numbers of dialysis sessions during pregnancy was 71.7%. The abortion rate was 22.4% in those with increased HD sessions, whereas 79.3% in those not increased HD sessions (p < 0.001). Live birth frequency was 67.2% in the increased HD sessions group and 3.4% in those who did not differ in HD sessions (p < 0.001). CONCLUSION: For the first time, we reported pregnancy outcomes in HD female patients, covering all regions of Turkey. It has been observed that; increasing the number of HD sessions in dialysis patients will decrease fetal and maternal complications and increase live birth rates.
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Dheir et al. (2021) conducted a cohort in Pregnancy in hemodialysis patients (n=145). Increased hemodialysis sessions vs. No increase in hemodialysis sessions was evaluated on Live birth frequency (p=<0.001). Increasing hemodialysis sessions during pregnancy was associated with a significantly higher live birth frequency (67.2% vs 3.4%, p<0.001) and a lower abortion rate (22.4% vs 79.3%, p<0.001).
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