Why the study?
Does food intake alter left ventricular wall stress in healthy subjects?
Observational (n=23)
No
Does food intake alter left ventricular wall stress in healthy subjects?
Food intake significantly decreases left ventricular end-systolic wall stress in healthy subjects, highlighting the importance of controlling for fasting state in echocardiographic studies.
Echocardiographic protocols should standardize fasting status for LV wall stress assessment; leaves open effects in cardiovascular disease.
OBJECTIVE: Left ventricular wall stress has been investigated in a variety of populations, but the effect of food intake has not been evaluated. We assessed whether left ventricular wall stress is affected by food intake in healthy subjects. METHODS: Twenty-three healthy subjects aged 25.6 ± 4.5 years were investigated. Meridional end-systolic wall stress (ESS) and circumferential end-systolic wall stress (cESS) were measured before, 30 minutes after, and 110 minutes after a standardised meal. RESULTS: Both ESS and cESS decreased significantly (P < 0.001) from fasting values 30 minutes after the meal, and had not returned to baseline after 110 minutes. ESS decreased from 65 ± 16 kdynes/cm2 (fasting) to 44 ± 12 kdynes/cm2 30 minutes after, and to 58 ± 13 kdynes/cm2 110 minutes after eating. cESS decreased from 98 ± 24 kdynes/cm2 to 67 ± 18 kdynes/cm2 30 minutes after, and to 87 ± 19 kdynes/cm2 110 minutes after the meal. CONCLUSION: This study shows that left ventricular wall stress is affected by food intake in healthy subjects.
No takes yet. Share an insight, caveat, or question.
Gårdinger et al. (2014) conducted an observational in Healthy subjects (n=23). Standardised meal (rice pudding) vs. Fasting state (baseline) was evaluated on Meridional end-systolic wall stress (ESS) at 30 minutes (p=<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:
More from Cardiovascular Ultrasound