Key result
Negative medication beliefs are linked to nearly 3-fold higher odds of cardiovascular non-adherence.
Why the study?
Poor adherence to vascular medications contributes considerably to CVD events and mortality, prompting an evaluation of patient beliefs and views affecting medication adherence in Greece.
Are negative medication beliefs associated with poor medication adherence in patients with cardiovascular and cardiometabolic disorders?
Cross-Sectional (n=1,988)
Yes
Are negative medication beliefs associated with poor medication adherence in patients with cardiovascular and cardiometabolic disorders?
Negative medication beliefs, concerns about drug efficacy, and preference for alternative therapies significantly increase the likelihood of medication non-adherence in patients with cardiovascular and cardiometabolic disorders.
Negative beliefs associated with non-adherence; supports screening but leaves open whether interventions improve adherence in cardiometabolic disease.
BACKGROUND: Evidence has shown that poor adherence to vascular medications contributes to a considerable proportion of all cardiovascular disease (CVD) events and mortality. The aim of the present work was to examine patients' beliefs/views that affect their level of adherence to the assigned medical treatment in the context of a multi-center study in Greece. METHODS: Between July 2022 and April 2023, 1988 patients (1180 females) with established cardiovascular disease or relevant cardiometabolic disorders were chosen from seven medical centers in Greece. The 4-item Morisky Medication Adherence Questionnaire gauged medication adherence and investigated patients' beliefs/views regarding treatment. RESULTS: Among participants, 51.2% showed perfect medication adherence, contrasting with 48.8% displaying poor adherence. Patients with negative medication beliefs were around three times more likely to be non-adherent (OR = 2.73; 95% CI = 2.28-3.28). Non-adherers held concerns about drug efficacy (OR = 2.34; 95% CI = 1.10-4.97) and favored alternative therapies (OR = 2.25; 95% CI = 1.75-2.91). CONCLUSION: The findings highlight the significance of addressing patient beliefs/views to improve medication adherence. The distinct Mediterranean context, influenced by cultural, socioeconomic, and clinical factors, emphasizes the need for tailored interventions. This underscores the call for contextually sensitive strategies to boost medication adherence and improve health outcomes in this unique region.
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Belitsi et al. (2023) conducted a cross-sectional in Cardiovascular disease and cardiometabolic disorders (n=1,988). Negative medication beliefs vs. Positive or neutral medication beliefs was evaluated on Poor medication adherence (OR 2.73, 95% CI 2.28-3.28). Patients with negative medication beliefs were approximately three times more likely to be non-adherent to their prescribed cardiovascular or cardiometabolic therapies (OR 2.73).
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