Key result
Among 69 patients with high-normal blood pressure, exaggerated blood pressure response to exercise was not associated with masked hypertension on 24-hour ambulatory monitoring.
Why the study?
Does an exaggerated blood pressure response to exercise predict masked hypertension in patients with high-normal resting blood pressure?
Observational (n=69)
No
Does an exaggerated blood pressure response to exercise predict masked hypertension in patients with high-normal resting blood pressure?
An exaggerated blood pressure response to exercise is not a reliable indicator of masked hypertension in patients with high-normal resting blood pressure.
Exaggerated exercise BP response should not prompt masked hypertension screening; leaves open need for larger studies on predictors in high-normal BP.
The association between exaggerated blood pressure (BP) response to exercise (ExBPR) and "masked hypertension" is unclear. Medical records of patients with high-normal BP who were evaluated in the Chaim Sheba Screening Institute Ramat Gan, Israel, during the years 2002-2007 and referred for 24-hour ambulatory BP monitoring (ABPM) and exercise test were reviewed. Data on exercise tests performed in the preceding 5 years were retrieved. Reproducible ExBPR was defined when it was recorded at least twice. BP levels on 24-hour ABPM were compared between patients with a normal BP response and those with an ExBPR (systolic BP ≥200 mm Hg). Sixty-nine normotensive patients with high normal BP levels were identified. ExBPR was recorded in 43 patients and was reproducible in 28. BP levels on 24-hour ABPM were similar in patients with and without ExBPR. In patients with high-normal BP levels, ExBPR is not associated with masked hypertension.
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Grossman et al. (2014) conducted an observational in High normal blood pressure (n=69). Exaggerated blood pressure response to exercise (ExBPR) vs. Normal blood pressure response to exercise was evaluated on Blood pressure levels on 24-hour ambulatory blood pressure monitoring (masked hypertension). Among 69 patients with high-normal blood pressure, exaggerated blood pressure response to exercise was not associated with masked hypertension on 24-hour ambulatory monitoring.
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