Key result
An exaggerated systolic pressure response to exercise (≥220 mm Hg) was associated with significantly higher 24-hour ambulatory systolic blood pressure (142 vs 127 mm Hg, P<0.01).
Why the study?
Does an exaggerated systolic pressure response to exercise correlate with higher 24-hour ambulatory blood pressure and altered left ventricular structure in sedentary subjects with high normal blood pressure?
Observational (n=30)
Does an exaggerated systolic pressure response to exercise correlate with higher 24-hour ambulatory blood pressure and altered left ventricular structure in sedentary subjects with high normal blood pressure?
In sedentary subjects with high normal blood pressure, an exaggerated systolic response to exercise is associated with significantly higher 24-hour ambulatory blood pressure but not with left ventricular hypertrophy.
Answers are grounded in this paper and cite their sources.
May indicate higher ambulatory BP in high-normal hypertension; hypothesis-generating, requires prospective validation before clinical use.
Few studies have investigated the significance of abnormal increases in systolic pressure during exercise in patients with high normal blood pressure and its correlation with 24-hour ambulatory blood pressure monitoring and left ventricular structure. This study was performed in 30 sedentary subjects (42 +/- 4 years old) with high normal blood pressure. Fifteen subjects presenting < 220 mm Hg systolic pressure during ergometric exercise were compared with 15 others with systolic pressure > or = 220 mm Hg. Average 24-hour (systolic, 127 +/- 5 versus 142 +/- 4 mm Hg, P < .01; diastolic, 82 +/- 4 versus 92 +/- 3 mm Hg, P < .01), daytime (systolic, 130 +/- 6 versus 144 +/- 4 mm Hg, P < .01; diastolic, 84 +/- 4 versus 92 +/- 4 mm Hg, P < .01), and nighttime (systolic, 116 +/- 7 versus 132 +/- 6 mm Hg, P < .01; diastolic, 72 +/- 6 versus 85 +/- 6 mm Hg, P < .01) ambulatory blood pressure monitoring values were significantly higher in subjects with an exaggerated blood pressure response to exercise. No significant differences were observed in left ventricular morphology. These findings indicate that subjects presenting high normal blood pressure and exaggerated systolic pressure during exercise show significantly high ambulatory blood pressure monitoring values that are not associated with left ventricular hypertrophy.
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Lima et al. (1995) conducted an observational in High normal blood pressure (n=30). Exaggerated systolic pressure response to exercise (≥ 220 mm Hg) vs. Systolic pressure < 220 mm Hg during exercise was evaluated on Average 24-hour systolic blood pressure (p=< .01). An exaggerated systolic pressure response to exercise (≥220 mm Hg) was associated with significantly higher 24-hour ambulatory systolic blood pressure (142 vs 127 mm Hg, P<0.01).
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