Microspheres, approximately 50 µ in diameter and labeled with scandium 46 , were injected into the jugular vein of seven anesthetized dogs. Each lobe of lung contained nearly equal counts per minute per gram of tissue. This suggests that the indicator was completely mixed with the blood by the time it arrived in the pulmonary artery, and that the perfusion rate of blood per gram of lung is nearly identical for all lobes.
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Hamlin et al. (1962) studied this question.
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