Key result
Addition of 5 mM or more orthophosphate to experimental solutions eliminated the most striking nonlinearity in the mechanical dynamics of glycerinated insect fibrillar flight muscle.
Population
glycerinated insect fibrillar flight muscle
Comparison
addition of 5 mM or more orthophosphate, ATP… vs experimental solutions without orthophosphate
Design
Preclinical
Authors
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Orthophosphate effects on insect muscle dynamics warrant targeted cardiac studies; leaves open translation to mammalian or clinical contexts.
Addition of orthophosphate to experimental solutions eliminates a key nonlinearity in insect fibrillar flight muscle dynamics, while ATP and ADP show opponent effects on mechanical rate constants.
White et al. (1972) studied Insect fibrillar flight muscle dynamics. Orthophosphate vs. Solutions without orthophosphate was evaluated on Nonlinear mechanical dynamics and oscillatory work. Addition of 5 mM or more orthophosphate to experimental solutions eliminated the most striking nonlinearity in the mechanical dynamics of glycerinated insect fibrillar flight muscle.
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