Key result
Cryoablation was associated with a significantly higher rate of sinus rhythm maintenance at 12 months compared to radiofrequency ablation (63.1% vs 37.8%, OR 2.41) in patients undergoing concomitant cardiac surgery.
Why the study?
Does surgical left atrial ablation (cryoablation vs radiofrequency) improve maintenance of sinus rhythm at 12 months in patients undergoing concomitant cardiac surgery for atrial fibrillation?
Cohort (n=376)
No
Does surgical left atrial ablation (cryoablation vs radiofrequency) improve maintenance of sinus rhythm at 12 months in patients undergoing concomitant cardiac surgery for atrial fibrillation?
Odds Ratio: 2.41 (95% CI 1.44–4.06)
Absolute Event Rate: 63.1% vs 37.8%
p-value: p=0.0021
In patients undergoing concomitant cardiac surgery, surgical left atrial ablation achieved a 48.9% sinus rhythm maintenance rate at 1 year, with cryoablation demonstrating significant superiority over radiofrequency ablation.
May support cryoablation preference in concomitant surgery; leaves open need for randomized confirmation.
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Mach et al. (2015) conducted a cohort in Atrial fibrillation (n=376). Cryoablation vs. Radiofrequency ablation was evaluated on Maintenance of sinus rhythm at 12 months (OR 2.41, 95% CI 1.44-4.06, p=0.0021). Cryoablation was associated with a significantly higher rate of sinus rhythm maintenance at 12 months compared to radiofrequency ablation (63.1% vs 37.8%, OR 2.41) in patients undergoing concomitant cardiac surgery.
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