Key result
Idiopathic paroxysmal atrial fibrillation was associated with significantly larger left atrial volume compared to healthy controls (27 vs 19 mL/m2; P<0.05).
Why the study?
Do patients with idiopathic paroxysmal atrial fibrillation have structural echocardiographic abnormalities compared to healthy controls?
Case-Control (n=120)
Do patients with idiopathic paroxysmal atrial fibrillation have structural echocardiographic abnormalities compared to healthy controls?
Absolute Event Rate: 27% vs 19%
p-value: p=<0.05
Patients with idiopathic paroxysmal atrial fibrillation have significantly larger left atria compared to healthy controls, suggesting an enhanced anatomical substrate for the arrhythmia.
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May indicate early remodeling in idiopathic paroxysmal AF; hypothesis-generating and requires prospective validation before clinical use.
Sitges et al. (2007) conducted a case-control in Idiopathic paroxysmal atrial fibrillation (n=120). Idiopathic paroxysmal atrial fibrillation vs. Healthy volunteers was evaluated on Left atrial volume (mL/m2) (p=<0.05). Idiopathic paroxysmal atrial fibrillation was associated with significantly larger left atrial volume compared to healthy controls (27 vs 19 mL/m2; P<0.05).
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