The macrophage is both a scavenger and a secretory cell. In both of its functions it facilitates immune responses by presenting antigen to lymphocytes in a form that heightens immunogenicity, by stimulating lymphocyte differentiation and proliferation, and by providing a stage for B-cell-T-cell interaction. Macrophages also can act under T-cell influence to destroy target bacterial and tumor cells.
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Emil R. Unanue (1979) studied this question.
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