Key result
Pharmacologic therapy for chronic heart failure has evolved from symptom relief to evidence-guided treatments like ACE inhibitors that target neurohormonal maladaptation to improve survival.
The review outlines the paradigm shift in heart failure treatment from hemodynamic correction to neurohormonal modulation.
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Neurohormonal therapies remain foundational in chronic HF; leaves open refinement of sequencing and novel targets.
Ramahi et al. (1995) conducted a review in Chronic heart failure. Pharmacologic therapy was evaluated. Pharmacologic therapy for chronic heart failure has evolved from symptom relief to evidence-guided treatments like ACE inhibitors that target neurohormonal maladaptation to improve survival.
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