The Journal of the American Medical Association

THE GROWING PROMINENCE OF URINARY CREATIN In reviewing the progress of diagnostic methods, one almost gains the impression of the existence of eras, as it were, in which the important advances have been confined largely to a single field of endeavor or a special type of technic. The progress of bacteriology emphasized the importance of the microscope as a help in diagnosis; the renewed study of the heart and the circulation has directed attention to the use of certain forms of physical apparatus like the manometer or pressure-gage; immunology is bringing the test-tube into competition once more with the section knife; while the modern advances in the field of nutrition study have made the chemical laboratory an indispensable adjunct to every scientific outfit in experimental medicine. It is no less interesting to watch how these shifting tendencies reflect themselves in the equipment of the practitioner. What one day is a highly