Key result
Elevated total vascular resistance was a strong independent predictor for the composite of maternal and fetal complications in early mild gestational hypertension (OR 64.4; 95% CI 25.9-160.1).
Why the study?
Does elevated total vascular resistance and concentric left ventricular geometry predict adverse maternal and fetal outcomes in women with early mild gestational hypertension?
Population
268 women with early mild gestational hypertension referred to the obstetrics outpatient clinic of Tor…
Design
Cohort
Authors
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Should not yet change practice in early mild gestational hypertension; leaves open whether vascular resistance assessment refines risk stratification.
Observational (n=268)
No
Does elevated total vascular resistance and concentric left ventricular geometry predict adverse maternal and fetal outcomes in women with early mild gestational hypertension?
Odds Ratio: 64.4 (95% CI 25.9–160.1)
Elevated total vascular resistance (>1340 dyn seconds/cm5) and concentric left ventricular geometry assessed by echocardiography strongly predict adverse maternal and fetal outcomes in women with early mild gestational hypertension.
Valensise et al. (2006) conducted an observational in Early mild gestational hypertension (n=268). Elevated total vascular resistance (TVR) vs. Lower total vascular resistance was evaluated on Composite of maternal and fetal complications (pre-eclampsia, preterm delivery, placental abruption, other maternal medical problems, fetal distress, neonatal low birthweight, admittance to neonatal intensive care unit and perinatal death) (OR 64.4, 95% CI 25.9-160.1). Elevated total vascular resistance was a strong independent predictor for the composite of maternal and fetal complications in early mild gestational hypertension (OR 64.4; 95% CI 25.9-160.1).
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