Key result
Regular athletic training in soccer players was associated with higher cardiac IGF-I formation and increased cardiac norepinephrine spillover compared to sedentary controls (P<0.01).
Why the study?
Does regular athletic training alter cardiac growth factor formation and sympathetic activity compared to a sedentary lifestyle in healthy men?
Population
30 healthy men, comprising 15 trained competitive soccer players and 15 sedentary control subjects of…
Comparison
Regular athletic training (competitive soccer) vs Sedentary lifestyle (no sporting activities)
Design
Cross-sectional
Authors
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Supports mechanistic hypotheses for IGF-I and sympathetic activity in athlete's heart; leaves open causality and requires prospective validation.
Cross-Sectional (n=30)
Does regular athletic training alter cardiac growth factor formation and sympathetic activity compared to a sedentary lifestyle in healthy men?
p-value: p=<0.01
Physiological cardiac hypertrophy in athletes performing predominantly isotonic exercise is associated with increased cardiac IGF-I formation and enhanced, heart-specific sympathetic activity.
Serneri et al. (2001) conducted a cross-sectional in Physiological hypertrophy (n=30). Regular athletic training (competitive soccer) vs. Sedentary control subjects was evaluated on Cardiac formation of insulin-like growth factor (IGF)-I and cardiac norepinephrine (NE) spillover (p=<0.01). Regular athletic training in soccer players was associated with higher cardiac IGF-I formation and increased cardiac norepinephrine spillover compared to sedentary controls (P<0.01).
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