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A literature search was conducted for evidence of natural selection having acted on PGI loci at two levels: (1) on polymorphisms, and (2) on homologous loci in closely related species during the speciation process. The results indicated that at both levels there is a significant relationship between relative electrophoretic mobility (probably net charge) and environmental conditions, such that the more anodal allozyme/isozyme is favoured under a suite of conditions comprising one or more of the following: increased temperature, increased salinity, increased exposure and risk of desiccation, and reduced oxygen availability.
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Bruce Riddoch (1993) studied this question.
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