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December 1, 1992The FASEB JournalOpen Access

Cytokine receptors and signal transduction

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Authors

TTTetsuya TagaTKTadamitsu Kishimoto

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Overview

Uncovers signal transduction in cytokine receptors, highlighting their complexity and integration in immune systems.

Key Points

  • The aim is to explore the characteristics and signaling mechanisms of newly identified cytokine receptors.
  • Review of newly cloned cytokine receptors and their structural classifications
  • Analysis of receptor-associated molecules facilitating ligand binding and signal transduction
  • Examination of phosphorylation events post-ligand stimulation.
  • New receptor families were identified based on structural similarities
  • Shared signal transduction molecules were found among different cytokine receptors
  • Phosphorylation of receptors and cytoplasmic proteins was common after ligand stimulation.

Cite This Study

Taga et al. (1992) studied this question.

synapsesocial.com/papers/6a202c72eaa49a33b5fc0289https://doi.org/10.1096/fasebj.6.15.1334470
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