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Mucosal immune dysregulation in mucosa-associated lymphoid tissues (MALT) drives the production of abnormally glycosylated, nephritogenic IgA1, which is central to the pathogenesis of IgA nephropathy and represents a target for emerging treatments. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

The role of mucosal immune dysregulation in the pathogenesis of immunoglobulin A nephropathy

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