Echo Doppler estimation of pulmonary artery systolic pressure correlated moderately with right heart catheterization (r = 0.62), with 51.9% of patients having a difference >10 mmHg.
Observational (n=69)
No
Does pulmonary capillary wedge pressure explain the discordance between echo Doppler and right heart catheterization estimates of pulmonary artery systolic pressure?
Pulmonary capillary wedge pressure is a significant covariate that helps explain the discordance between echocardiographic and invasive measurements of pulmonary artery systolic pressure.
Effect estimate: r = 0.62
BACKGROUND: Although the echo Doppler (D) estimation of pulmonary artery systolic pressure (PASP) was initially highly correlated with right heart catheterization (RHC), recent D-RHC studies have questioned its accuracy. The aim of this study was to reevaluate this relationship and to determine possible explanations for disparate D-RHC results. METHODS: We retrospectively identified all patients at one institution who underwent RHC and had an echocardiogram within the prior month. Echocardiographic and catheterization hemodynamic factors were evaluated by regression and Bland-Altman analysis. RESULTS: Of 69 patients, 52 (75.4%) had estimable D-PASP. D-RHC PASP r = 0.62 and 51.9% had a PASP difference >10 mmHg, comparable to other recent studies. The D-RHC difference correlated with pulmonary capillary wedge pressure (PCWP) (r = -0.60, P < 0.001) and right atrial pressure (r = -0.43, P = 0.002). Multivariate analysis including wedge pressure improved the relation between D and RHC for PASP (r = 0.86). These results were little changed using only the respective RV-RA pressure gradients from D and RHC. CONCLUSION: Pulmonary capillary wedge pressure appears to be a significant covariate in the correlation between D and RHC PASP.
Finkelhor et al. (Fri,) conducted a observational in Hemodynamic assessment (n=69). Echo Doppler estimation of pulmonary artery systolic pressure vs. Right heart catheterization was evaluated on Correlation between Doppler and right heart catheterization pulmonary artery systolic pressures (r = 0.62). Echo Doppler estimation of pulmonary artery systolic pressure correlated moderately with right heart catheterization (r = 0.62), with 51.9% of patients having a difference >10 mmHg.