The nature and distribution of two types of fibers in the rat diaphragm with respect to its dorsal (vertebral), lateral (costal), and the ventral (sternal) regions, have been studied. 2. Histochemical as well as quantitative studies on the fat and glycogen contents and the enzymic activity (lipase and succinic dehydrogenase) have been made in the above three regions. 3. It is concluded that the narrow red type of fibers is well adapted for aerobic metabolism, involving mainly the oxidation of fat for energy, and the other, the broad white variety, for anaerobic metabolism where glycogen is the chief fuel. The significance of the regional differences in the two types of fibers in the physiology of the diaphragm is discussed.
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George et al. (1961) studied this question.
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