The study provides physiological evidence that aortic pressure moduli increase peripherally due to increasing stiffness, with phase velocities converging to 5 m/sec at higher frequencies.
May inform aortic wave propagation models; leaves open clinical validation in human cohorts.
Pressures at various points of the human aorta were recorded and resolved into their sinusoidal components by Fourier analysis. A progressively decreasing phase angle with distance along the aorta was found. This was considered compatible with a traveling wave system. The pressure moduli generally increased with distance along the aorta. This was attributed to the progressively increasing stiffness of the aorta peripherally. Minor undulations in moduli could be explained on the basis of superimposed reflections. The apparent phase velocities were calculated for various points along the aorta. They tended to converge at higher frequencies to a value of 5 m/sec.
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Luchsinger et al. (1964) studied this question.
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