Why the study?
What produces the deep Q waves on the electrocardiogram in patients with hypertrophic cardiomyopathy?
What produces the deep Q waves on the electrocardiogram in patients with hypertrophic cardiomyopathy?
Deep Q waves in hypertrophic cardiomyopathy appear to be caused by the activation of the hypertrophied septum, which exhibits distinct electrophysiologic properties.
May explain Q waves in HCM via septal activation; leaves open prospective validation of distinct myopathic properties.
IN patients with hypertrophic cardiomyopathy the electrocardiogram often displays deep Q waves that may suggest myocardial infarction.1 2 3 Some investigators have ascribed these Q waves to the activation of the hypertrophied interventricular septum,4 , 5 but others think that they may be due to fibrosis of the septal tissue.6 We have performed an electrophysiologic study of ventricular activation in six patients with hypertrophic cardiomyopathy, normal coronary arteries, and deep Q waves on the electrocardiogram. Our findings suggest that the Q waves are produced by the activation of the septum and that myopathic septal muscle has different electrophysiologic properties from those of the remainder . . .
No takes yet. Share an insight, caveat, or question.
Cosío et al. (1980) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: