Parkinson's Syndrome

Neurosurgical Procedures in Parkinson's DiseaseAfter fifty years of varied but unsuccessful attacks by neurosurgeons a most stimulating advance was begun about twenty years ago, when Russell Meyers45 reported his investigations on the ansa lenticularis. Since then it has become clear that tremor and rigidity may be significantly altered by lesions in the mesial aspect of the globus pallidus, the ventrolateral nucleus of the thalamus and the substantia nigra and midbrain tegmentum. Various methods of destruction are used, including alcohol in methylcellulose,46 a leukotome,47 electrocoagulation,48 procaine in beeswax,49 radioactive palladium50 and focused ultrasound.51 The areas mentioned may be approached from . . .