Key result
Women with acute myocardial infarction had a higher 30-day readmission rate than men (22.1% vs. 7.8%), but this difference was no longer significant after adjusting for social factors (OR 0.87).
Why the study?
Women with AMI have a higher prevalence of unfavorable social variables and worse outcomes than men, but the impact of these social variables on 30-day readmission is less understood.
Does female gender and associated social hardships increase all-cause 30-day readmission in adult patients with acute myocardial infarction?
Cohort (n=208)
No
Does female gender and associated social hardships increase all-cause 30-day readmission in adult patients with acute myocardial infarction?
Odds Ratio: 3.34 (95% CI 1.1–11.1)
Absolute Event Rate: 22.1% vs 7.8%
p-value: p=0.049
Higher 30-day readmission rates among women with acute myocardial infarction appear to be driven by unfavorable social factors rather than clinical differences.
Social factors may explain higher readmission rates among women after AMI; leaves open whether targeted interventions improve outcomes.
Background: Studies have shown that women with acute myocardial infarction (AMI) have a higher prevalence of unfavorable social variables then men and have a worse outcome. Less is known regarding the impact of these social variables on 30-day readmission after AMI. Materials and Methods: We analyzed adult patients with AMI enrolled in a Quality Improvement Program intended to improve the peri-discharge care of patients with an AMI, and decrease all-cause 30-day unplanned readmissions. We compared clinical and social variables by gender. Multivariate logistic regression, with separate adjustment for clinical and for social variable, was used to measure adjusted odds for readmission by gender. Results: Among 208 patients included in our project 68 (32.7%) were women. Only 30.9% of women were married or had domestic partner at the time of the interview and only 16.2% were employed. Nearly half of women (48.5%) needed help with medical care, and 39.7% of women did not speak English as their first language. These variables were significantly different by gender. Rates of 30-day readmissions were higher in women than men (22.1% vs. 7.8%, p = 0.024). After adjusting for clinical variables this difference by gender in 30-day readmissions remained significant (odds ratio [OR] 3.34 95% confidence interval [CI] 1.1–11.1, p = 0.049). However, when adjusting for social variables, this difference was no longer noted (OR 0.87 95% CI 0.27–2.78, p = 0.822). Conclusion: Women with AMI are more likely than men to have unfavorable social factors that can impact recovery from AMI and women have a higher 30-day readmission rate. The higher 30-day readmissions in women appears to be influenced by these social factors. Health care interventions aimed at reducing 30-day readmission after AMI should focus on eliciting a detailed social history and providing aid for those requiring additional social support at home.
No takes yet. Share an insight, caveat, or question.
Haddadin et al. (2022) conducted a cohort in Acute Myocardial Infarction (n=208). Female gender vs. Male gender was evaluated on All-cause 30-day readmission (OR 3.34, 95% CI 1.1-11.1, p=0.049). Women with acute myocardial infarction had a higher 30-day readmission rate than men (22.1% vs. 7.8%), but this difference was no longer significant after adjusting for social factors (OR 0.87).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: