Key result
Continuous anesthetic wound infusion did not significantly increase the recovery rate of postoperative activity on day 4 compared to control (58% vs. 44%, p=0.450) in patients undergoing midline laparotomy.
Why the study?
It was unknown whether continuous anesthetic wound infusion increases postoperative activity in patients undergoing midline laparotomy for gynecological diseases.
Does continuous anesthetic wound infusion increase postoperative activity in patients who undergo midline laparotomy for gynecological diseases?
Observational (n=22)
No
Does continuous anesthetic wound infusion increase postoperative activity in patients who undergo midline laparotomy for gynecological diseases?
Continuous anesthetic wound infusion was not associated with a significant increase in postoperative activity compared to patient-controlled analgesia alone in patients undergoing midline laparotomy for gynecological diseases.
No support for routine wound infusion use after gynecological laparotomy; leaves open efficacy in randomized trials.
Objective This study aimed to assess whether continuous anesthetic wound infusion (CAWI) increases postoperative activity in patients who undergo midline laparotomy for gynecological diseases. Methods This was an unplanned secondary analysis of a randomized controlled trial examining the effect of an activity tracker with feedback on postoperative activity in patients who underwent midline laparotomy for gynecological diseases ( NCT02025387 ). Of the 53 patients included in the trial (12 patients used CAWI and 41 patients did not), 11 patients with CAWI (case group) and 11 without CAWI (control group) were selected by matching the duration of surgery. We compared the postoperative activity and other endpoints between the case and control groups. Results The case and control groups had similar baseline and surgical characteristics. The recovery rate on postoperative day 4 (step counts at day 4/ daily step counts at preoperative baseline) of the case group was numerically higher, but not significantly different from that of the control group (58% vs. 44%; p=0.450). Least, average and present pain on postoperative day 2 were lower in the case group than in the control group. Pain on postoperative day 5, fatigue, gas out, soft blend diet initiation, ileus, and length of hospital stay were similar between the case and control groups. Conclusions In this exploratory analysis, CAWI was not associated with increased postoperative activity in patients who underwent midline laparotomy for gynecological diseases.
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Kim et al. (2023) conducted an observational in Midline laparotomy for gynecological diseases (n=22). Continuous anesthetic wound infusion (CAWI) vs. Intravenous patient-controlled analgesia (PCA) alone was evaluated on Recovery rate on postoperative day 4 (step counts at day 4 divided by daily step counts at preoperative baseline) (p=0.450). Continuous anesthetic wound infusion did not significantly increase the recovery rate of postoperative activity on day 4 compared to control (58% vs. 44%, p=0.450) in patients undergoing midline laparotomy.
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