Key result
Subxiphoid pericardiostomy effectively treated massive pericardial effusion with no recurrences, and pericardial thickness significantly predicted the development of constrictive pericarditis (p=0.004).
Why the study?
Is subxiphoid pericardiostomy effective for treating massive pericardial effusion, and what predicts the development of constrictive pericarditis?
Cohort (n=32)
No
Is subxiphoid pericardiostomy effective for treating massive pericardial effusion, and what predicts the development of constrictive pericarditis?
p-value: p=0.004
Subxiphoid pericardiostomy is an effective treatment for massive pericardial effusion with no observed recurrence, though patients with thickened pericardium are at significant risk for developing constrictive pericarditis.
Subxiphoid pericardiostomy may be considered for massive pericardial effusion given no observed recurrences; this Level 3 cohort finding leaves open pericardial thickness as a predictor pending prospective validation.
Background. The diagnosis and treatment of massive pericardial effusion and cardiac tamponade have evolved over the years with a tendency towards a more comprehensive diagnostic workup and less traumatic intervention. Method. We reviewed and analysed the data of 32 consecutive patients who underwent surgery on account of massive pericardial effusion and cardiac tamponade in a semiurban university hospital in Nigeria from February 2010 to February 2016. Results. The majority of patients (34.4%) were between 31 and 40 years. Fourteen patients (43.8%) presented with clinical and echocardiographic feature of cardiac tamponade. The majority of patients (59.4%) presented with haemorrhagic pericardial effusion and the average volume of fluid drained intraoperatively was 846 mL ± 67 mL. Pericardium was thickened in 50% of cases. Subxiphoid pericardiostomy was performed under local anaesthesia in 28 cases. No postoperative recurrence was observed; however 5 patients developed features of constrictive pericarditis. The relationship between pericardial thickness and development of pericardial constriction was statistically significant (p = 0.004). Conclusion. Subxiphoid pericardiostomy is a very effective way of treating massive pericardial effusion. Removing tube after adequate drainage (50 mL/day) and treatment of primary pathology are key to preventing recurrence. There is also a need to follow up patients to detect pericardial constriction especially those with thickened pericardium.
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Kesieme et al. (2016) conducted a cohort in Massive pericardial effusion and cardiac tamponade (n=32). Surgery (Subxiphoid pericardiostomy) was evaluated on Development of constrictive pericarditis (p=0.004). Subxiphoid pericardiostomy effectively treated massive pericardial effusion with no recurrences, and pericardial thickness significantly predicted the development of constrictive pericarditis (p=0.004).
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