Why the study?
Do new ECG criteria improve the diagnostic accuracy of right ventricular hypertrophy in patients with mitral stenosis compared to Bonner's and Mortara's criteria?
Do new ECG criteria improve the diagnostic accuracy of right ventricular hypertrophy in patients with mitral stenosis compared to Bonner's and Mortara's criteria?
The proposed ECG criteria for diagnosing right ventricular hypertrophy in mitral stenosis offer higher accuracy than existing automated criteria like Bonner's and Mortara's.
May support refined ECG screening for RVH in mitral stenosis; leaves open prospective validation before clinical adoption.
New criteria for the diagnosis of right ventricular hypertrophy (RVH) using a point scoring system were developed after analyzing standard 12-lead ECGs in 155 patients with mitral stenosis verified by cardiac catheterization and 155 age and sex-matched apparently normal healthy subjects. ECGs were evaluated to identify criteria that provided maximum sensitivity and at least a 95% specificity: (1) the R wave magnitude in V1 had to be greater than 0.7 mV; (2) the S wave magnitude in V6 had to be greater than 0.3 mV; (3) the S wave magnitude in V1 less than 0.5 mV; (4) the R wave magnitude in V1 plus the S wave magnitude in V6 minus the S wave magnitude in V1 must be greater than 0 mV; and (5) the degree of frontal QRS axis had to be greater than 90 degrees. Application of these criteria achieved 25% (39 of 155) sensitivity in patients with RVH, significantly better (p less than 0.01) than the 17% sensitivity (17 of 155) of Bonner's criteria for the automated ECG. The specificity of the proposed criteria was 98% (152 of 155), significantly better (p less than 0.01) than the 90% specificity (139 of 155) of Mortara's criteria. Thus, it was evident that the accuracy of the proposed criteria was the highest among those criteria used in a point scoring system including the currently used automated ECG criteria for the diagnosis of RVH.
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Hiroki et al. (1988) studied this question.
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