On the Calculation of "Turnover Time" and "Turnover Rate" From Experiments Involving the Use of Labeling Agents

A new method for the determination of an immediate precursor of a substance occurring in the animal body is presented. 2. Calculations on the quantitative determination of the rate of turnover of a substance and their application to experiments involving the use of labeling agents are given. These calculations take into account loss of the isotopic substance by way of breakdown or transport.