An oral glucose tolerance test is the preferred screening method for detecting early glucose abnormalities in women with polycystic ovary syndrome.
What is the preferred method for screening for glucose intolerance in women with polycystic ovary syndrome?
The oral glucose tolerance test is the preferred screening method for early detection of glucose abnormalities in women with PCOS to prevent progression to T2D and modify cardiovascular risk.
Polycystic ovary syndrome (PCOS) is a chronic condition with many reproductive, metabolic and psychological manifestations. Insulin resistance puts women with PCOS at an increased risk for developing impaired glucose tolerance (IGT) and diabetes (T2D). An oral glucose tolerance test is the preferred IGT/T2D screening test, since it is most sensitive for detecting early glucose abnormalities. The goals in detecting IGT in these women are to avoid progression to T2D, modify cardiovascular risk and prevent gestational diabetes. Periodic IGT/T2D rescreening is necessary, given their propensity for more rapid deterioration in glucose tolerance. Lifestyle intervention is first-line therapy for PCOS women with IGT. Metformin is an option if lifestyle intervention fails to have an impact, while bariatric surgery is reserved for a select set of morbidly obese patients.
Kelley et al. (Fri,) conducted a review in Polycystic ovary syndrome (PCOS). Oral glucose tolerance test was evaluated. An oral glucose tolerance test is the preferred screening method for detecting early glucose abnormalities in women with polycystic ovary syndrome.