What question did this study set out to answer?

Examine the emergence and spread of EMRSA-16 phage variants in hospitals in England and Wales over two years.

Emergence, Spread, and Characterization of Phage Variants of Epidemic Methicillin-Resistant Staphylococcus aureus 16 in England and Wales

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Randomized trial describes the emergence and spread of EMRSA-16 phage variants in hospitals, indicating significant public health concerns.

Examine the emergence and spread of EMRSA-16 phage variants in hospitals in England and Wales over two years.
Analyzed 129 clinical isolates from 52 hospitals over 18 months.
Used phage typing, PFGE, antimicrobial susceptibility tests, and PCR for toxin gene detection.
Collected isolates representing classical EMRSA-16 and its phage variants.
Identified 29 PFGE profiles, indicating genetic diversity among strains.
More prevalent in males aged 60-80 years; isolated mainly from sputum and throat.
Phage variants exhibited similar characteristics to classical EMRSA-16, but relationships were inferred without genotyping.

Murchan et al. (2004) studied this question.

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Randomized trial describes the emergence and spread of EMRSA-16 phage variants in hospitals, indicating significant public health concerns.