Percutaneous transvenous mitral commissurotomy significantly increased mitral valve area from 0.63 to 1.83 cm2 and achieved a 97.7% success rate in patients with severe mitral stenosis.
Cross-Sectional (n=90)
No
Does percutaneous transvenous mitral commissurotomy (PTMC) improve mitral valve area and hemodynamics in patients with severe mitral stenosis?
PTMC is a highly successful and safe procedure for improving valve area and hemodynamics in appropriately selected patients with severe mitral stenosis.
Absolute Event Rate: 1.83% vs 0.63%
p-value: p=<0.001
Objectives: To evaluate the immediate outcomes of PTMC in patients with severemitral valve stenosis. Study Design: Cross-sectional study. Setting: Ninety (90) subjects whounderwent PTMC in Cardiac Catheterization Department of CPE Institute of Cardiology. Period:June 2008 to June 2011. Methods: Patients with severe MS having mitral valve (MV) area <1.0cm2 and having morphology suitable for PTMC in the absence of regurgitation and left atrial clotwere included in this study. An increase in mitral valve area more than 50% of the baseline areawithout the development of moderate to severe MR was considered as the procedural success.Data were analyzed using SPSS V19. Pre and post procedural outcomes were measured usingpaired sample t-test. Results: There were a total number of ninety (90) patients in this study.Mean age of subjects was 28.08+9.61 years. There were more females 59 (65.5%) as comparedto only 31 (34.5%) males. There was significant increase in mitral valve area, 1.83+0.36 cm2post-PTMC versus 0.63+0.17 cm2 pre-PTMC (p-value <0.001). There was significant decreasein Peak pressure gradient (PPG) from 28.31+6.01 mmHg to 12.85+3.20 mmHg after PTMC(p-value <0.001). There were also significant reductions in mean pressure gradient andpulmonary artery systolic pressures after PTMC with p-value <0.001 and <0.001 respectively.PTMC was successful in 87 (97.7%) patients and it failed in only 3 (3.3%) patients. Conclusion:PTMC is an excellent treatment option regarding optimal outcomes and success rate in patientsof severe mitral stenosis especially when performed by experienced interventionists.
Babar et al. (2017) conducted a cross-sectional in Severe mitral valve stenosis (n=90). Percutaneous transvenous mitral commissurotomy (PTMC) vs. Pre-procedure baseline was evaluated on Mitral valve area (cm2) (p=<0.001). Percutaneous transvenous mitral commissurotomy significantly increased mitral valve area from 0.63 to 1.83 cm2 and achieved a 97.7% success rate in patients with severe mitral stenosis.