Key result
A novel echocardiographic visual score of aortic valve morphology significantly correlated with MSCT-derived calcium scores (r=0.496) and accurately predicted severe aortic stenosis with high specificity.
Why the study?
The diagnostic value of a visual assessment of aortic valve morphology for grading aortic stenosis remains unclear.
Does a visual score of aortic valve morphology using 2D echocardiography accurately detect and grade aortic stenosis compared to Doppler measurements and MSCT calcium scoring in adult patients?
Cross-Sectional (n=137)
Single-blind
No
Does a visual score of aortic valve morphology using 2D echocardiography accurately detect and grade aortic stenosis compared to Doppler measurements and MSCT calcium scoring in adult patients?
A novel 2D echocardiography visual score of aortic valve morphology provides a specific, easily applicable tool to detect and grade aortic stenosis, correlating well with Doppler hemodynamics and MSCT calcium scores.
The diagnostic value of a visual assessment of aortic valve (AV) morphology for grading aortic stenosis (AS) remains unclear. A visual score (VS) for assessing the AV was developed and its reliability with respect to Doppler measurements and the calcium score (ctCS) derived by multislice computed tomography was evaluated. 99 Patients with AS of various severity and 38 patients without AS were included in the analysis. Echocardiographic studies were evaluated using the new VS which includes echogenicity, thickening, localization of lesions and leaflet mobility, with a total score ranging from 0 to 11. The association of VS with ctCS and the severity of AS was analyzed. There was a significant correlation of VS with AV hemodynamic parameters and with ctCS. The cut-off value for the detection of AS of any grade was a VS of 6 (sensitivity 95%, specificity 85% for women; sensitivity 85%, specificity 88% for men). A VS of 9 for women and of 10 for men was able to predict severe AS with a high specificity (96% in women and 94% in men, AUC 0.8 and 0.86, respectively). The same cut-off values were identified for the detection of ctCS of ≥ 1600 AU and ≥ 3000 AU with a specificity of 77% and 82% (AUC 0.69 and 0.81, respectively). Assessment of aortic valve morphology can serve as an additional diagnostic tool for the detection of AS and an estimation of its severity.
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Nemchyna et al. (2020) conducted a cross-sectional in Aortic stenosis (n=137). Visual assessment of aortic valve morphology (Visual Score) vs. Doppler echocardiography and MSCT-derived calcium score was evaluated on Correlation between Visual Score and MSCT-derived calcium score (r = 0.496, p=<0.0001). A novel echocardiographic visual score of aortic valve morphology significantly correlated with MSCT-derived calcium scores (r=0.496) and accurately predicted severe aortic stenosis with high specificity.
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