Ablation with the ThermoCool Surround Flow catheter increased the rate of pulmonary veins remaining isolated 30 minutes post-ablation compared to the ThermoCool catheter (95.2% vs 90.5%, P<0.03).
RCT (n=106)
one-to-one
Yes
Does radiofrequency ablation using the ThermoCool Surround Flow catheter improve persistent electrical isolation of pulmonary veins in patients with paroxysmal atrial fibrillation compared to the standard ThermoCool catheter?
The ThermoCool Surround Flow catheter improves early persistent electrical isolation of pulmonary veins and reduces infused saline volume compared to the standard ThermoCool catheter during paroxysmal AF ablation.
Absolute Event Rate: 95.2% vs 90.5%
p-value: p=< 0.03
Persistent Electrical Isolation of Pulmonary Veins . Introduction: Aim of this study was to compare efficacy and safety of the new ThermoCool Surround Flow® catheter (SFc) versus the ThermoCool® (TCc) in achieving persistent circumferential electrical isolation of the pulmonary veins (PVs) in patients with paroxysmal atrial fibrillation (AF). Methods and Results: This multicenter, randomized, controlled study enrolled patients suffering from paroxysmal AF. Randomization was run in a one‐to‐one fashion between radiofrequency ablation by TCc or SFc. Aim of PVs ablation was documentation of electrical isolation with exit/entrance block recorded on a circular catheter. Among the 106 enrolled patients, 52 (49.0%) were randomized to TCc and 54 (51.0%) to SFc. Total volume of infused saline solution during the procedure was lower in the SFc than in TCc group (752.7 ± 268.6 mL vs 1,165.9 ± 436.2 mL, P < 0.0001). Number of identified and isolated PVs was similar in the 2 groups. Number of PVs remaining isolated 30 minutes after ablation was higher in the SFc than in TCc group (95.2% vs 90.5%, P < 0.03), mainly driven by acute ablation result in the left PVs (96.1% vs 89.7%, P < 0.04). Complications were seldom and observed only in the TCc group (0% vs 3.84%, P < 0.03). At 6‐month follow‐up SFc patients reported a trend toward less AF recurrences compared to those in the TCc group (22.9% vs 27.0%, P = 0.69). Conclusion: PV isolation by SFc lowered the rate of left PV early reconnections and reduced the volume of infused saline solution while maintaining the safety profile of AF ablation. (J Cardiovasc Electrophysiol, Vol. 24, pp. 269‐273, March 2013)
Bertaglia et al. (Wed,) conducted a rct in paroxysmal atrial fibrillation (n=106). ThermoCool Surround Flow catheter (SFc) vs. ThermoCool catheter (TCc) was evaluated on Pulmonary veins remaining isolated 30 minutes after ablation (p=< 0.03). Ablation with the ThermoCool Surround Flow catheter increased the rate of pulmonary veins remaining isolated 30 minutes post-ablation compared to the ThermoCool catheter (95.2% vs 90.5%, P<0.03).