Three weeks of high-intensity interval training improved insulin sensitivity (HOMA-IR) in overweight/obese men compared to control (MD -2.78 units; p < 0.05).
RCT (n=25)
randomly assigned
Mean Difference: -2.78
p-value: p=< 0.05
INTRODUCTION: High-intensity interval training (HIIT) is a time-efficient strategy shown to induce various cardiovascular and metabolic adaptations. Little is known about the optimal tolerable combination of intensity and volume necessary for adaptations, especially in clinical populations. OBJECTIVES: In a randomized controlled pilot design, we evaluated the effects of two types of interval training protocols, varying in intensity and interval duration, on clinical outcomes in overweight/obese men. METHODS: Twenty-five men body mass index (BMI) > 25 kg · m(2) completed baseline body composition measures: fat mass (FM), lean mass (LM) and percent body fat (%BF) and fasting blood glucose, lipids and insulin (IN). A graded exercise cycling test was completed for peak oxygen consumption (VO2peak) and power output (PO). Participants were randomly assigned to high-intensity short interval (1MIN-HIIT), high-intensity interval (2MIN-HIIT) or control groups. 1MIN-HIIT and 2MIN-HIIT completed 3 weeks of cycling interval training, 3 days/week, consisting of either 10 × 1 min bouts at 90% PO with 1 min rests (1MIN-HIIT) or 5 × 2 min bouts with 1 min rests at undulating intensities (80%-100%) (2MIN-HIIT). RESULTS: There were no significant training effects on FM (Δ1.06 ± 1.25 kg) or %BF (Δ1.13% ± 1.88%), compared to CON. Increases in LM were not significant but increased by 1.7 kg and 2.1 kg for 1MIN and 2MIN-HIIT groups, respectively. Increases in VO2peak were also not significant for 1MIN (3.4 ml·kg(-1) · min(-1)) or 2MIN groups (2.7 ml · kg(-1) · min(-1)). IN sensitivity (HOMA-IR) improved for both training groups (Δ-2.78 ± 3.48 units; p < 0.05) compared to CON. CONCLUSION: HIIT may be an effective short-term strategy to improve cardiorespiratory fitness and IN sensitivity in overweight males.
Smith‐Ryan et al. (Fri,) conducted a rct in overweight/obese (n=25). High-intensity interval training (1MIN-HIIT and 2MIN-HIIT) vs. Control was evaluated on Insulin sensitivity (HOMA-IR) (MD -2.78, p=< 0.05). Three weeks of high-intensity interval training improved insulin sensitivity (HOMA-IR) in overweight/obese men compared to control (MD -2.78 units; p < 0.05).