Why the study?
Does the use of calcium channel blockers or loop diuretics compared to beta blockers affect MRI white matter hyperintensity and cognitive impairment in older adults with treated hypertension?
Does the use of calcium channel blockers or loop diuretics compared to beta blockers affect MRI white matter hyperintensity and cognitive impairment in older adults with treated hypertension?
In older adults with treated hypertension, the use of calcium channel blockers or loop diuretics is associated with more severe MRI white matter hyperintensity and worse cognitive performance compared to beta blockers.
No takes yet. Share an insight, caveat, or question.
Should not yet change antihypertensive selection in older adults; leaves open whether beta blockers differentially protect white matter and cognition versus other agents.
Heckbert et al. (1997) studied this question.
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