Partner up! Base-pairing properties of oligo-dipeptides tagged with orotic acid and its 2,4-diamino counterpart (see structure) are found to be consistent with previously observed correlations between ΔpKa values and the pairing strength of complementary bases. The combined results provide a general justification for anticipating the base-pairing propensity of a recognition element based on its pKa value and the pH of the medium.
No takes yet. Share an insight, caveat, or question.
Zhang et al. (2009) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: