Invasive Adenoma of the Pituitary Gland and Chronic Migrainous Neuralgia. A Rare Coincidence or a Causal Relationship?

After 31 years of suffering from headache attacks which in the last five years were indistinguishable from migrainous neuralgia (cluster headache), a 52-year-old man was treated for an invasive adenoma of the pituitary gland. During a two-year follow-up period he has not had one single attack of his usual headache. The case history may suggest a causal relationship between the adenoma and the headache attacks.