January 1, 2016

Sunlight-promoted cyclization versus decarboxylation in the reaction of alkynoates with N-iodosuccinimide: easy access to 3-iodocoumarins

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Abstract

We report the green, sunlight-initiated radical conversion of aryl alkynoates to 3-iodocoumarins using NIS without the use of a catalyst or additive. Mechanistic studies indicate that the reaction proceeds through iodination, spirocyclization and ring expansion to form the kinetic product.

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Ni et al. (Fri,) studied this question.

synapsesocial.com/papers/6a20bb521d1b409c7a11d23d https://doi.org/https://doi.org/10.1039/c6gc01027j

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