Key result
Noninvasive positive-pressure ventilation during walking significantly increased arterial oxygen tension by 1.39 kPa, compared to a 1.43 kPa decrease without NPPV.
Why the study?
Does noninvasive positive-pressure ventilation during walking improve oxygenation, dyspnoea, and walking distance in patients with severe COPD?
RCT (n=20)
cross-over
Does noninvasive positive-pressure ventilation during walking improve oxygenation, dyspnoea, and walking distance in patients with severe COPD?
Absolute Event Rate: 1.39% vs -1.43%
In patients with severe COPD, using noninvasive positive-pressure ventilation during walking improves oxygenation, reduces dyspnoea, and increases walking distance.
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Supports NPPV during walking in severe COPD; extends prior evidence to ambulatory settings.
Dreher et al. (2007) conducted an RCT in severe chronic obstructive pulmonary disease (COPD) (n=20). Noninvasive positive-pressure ventilation (NPPV) vs. Without NPPV was evaluated on Change in arterial oxygen tension (kPa). Noninvasive positive-pressure ventilation during walking significantly increased arterial oxygen tension by 1.39 kPa, compared to a 1.43 kPa decrease without NPPV.
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