Key result
Among 1,300 patients in the Iranian Registry of Atrial Fibrillation, oral anticoagulation was prescribed to 69.5% of eligible patients, while aspirin was used in 35%.
Why the study?
Data on demographic features, clinical characteristics, associated comorbidities, and practice patterns of AF in Iran were lacking.
Cohort (n=1,300)
The IRAF registry provides contemporary baseline data on AF management in Iran, highlighting that while anticoagulation is used in nearly 70% of eligible patients, aspirin use remains common.
Suggests anticoagulation gaps in Iranian AF; hypothesis-generating for regional barriers and requires prospective studies before practice change.
Background Atrial fibrillation. (AF) is the most common sustained arrhythmia globally and its prevalence is likely to increase in the next decades as a result of increasing age and co-morbidities. There are no data on demographic features, clinical characteristics, associated comorbidities, and practice patterns of AF in Iran. Methods The Iranian Registry of Atrial Fibrillation (IRAF) is a hospital-based prospective survey of AF patients with a 12-month follow-up. Data were collected on a standardized case report form and entered into a web-based electronic database. This paper reports the baseline characteristics of the IRAF cohort. Results Between February 2018 and March 2020, a total of 1300 patients (57% Male, mean age, 60 ± 14 years) were enrolled. Palpitations were the most common presenting symptom (66%). The most common cardiac comorbidities were hypertension (52%), heart failure (23.7%), and valvular heart disease (21.8%). AF mainly presented as a paroxysmal pattern (44.6%). Seventy-eight percent of the patients with non-valvular AF had CHA2DS2-VASc score ≥1 and most (97%) were at low risk for bleeding (HAS-BLED score <3). Rhythm control was given to 55.1% of the patients. Anticoagulation for stroke prevention was provided to 69.5% of the eligible patients, while aspirin was used in 35%. Conclusion The IRAF Registry has provided a systematic collection of contemporary data regarding the management and treatment of AF in Iran. Oral anticoagulant was used in 69.5%, but aspirin use was still common.
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Heidarali et al. (2021) conducted a cohort in Atrial fibrillation (n=1,300). Atrial fibrillation was evaluated on Baseline characteristics and practice patterns. Among 1,300 patients in the Iranian Registry of Atrial Fibrillation, oral anticoagulation was prescribed to 69.5% of eligible patients, while aspirin was used in 35%.
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