Beta-2-microglobulin (beta 2-m) is an intrinsic part of the HLA system and is most probably involved in cell recognition. The levels of free beta 2-m in the blood and urine are influenced by beta 2-m production and its clearance and destruction in the kidney. Many tumors can be associated with an elevated serum beta 2-m, the reason is unknown. The most promising application of beta 2-m as a tumor marker would appear to be lymphoid malignancies, especially multiple myeloma and chronic lymphocytic leukemia.
No takes yet. Share an insight, caveat, or question.
Cooper et al. (1980) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: