Why the study?
The prognostic role of artificial intelligence using advanced cardiac magnetic resonance imaging in patients with cardiovascular disease remains unclear.
Does artificial intelligence in cardiovascular magnetic resonance predict outcomes in patients with cardiovascular disease?
Systematic Review (n=3,679)
Does artificial intelligence in cardiovascular magnetic resonance predict outcomes in patients with cardiovascular disease?
Hazard Ratio: 2.02 (95% CI 1.47–2.58)
p-value: p=<0.001
Artificial intelligence applied to cardiovascular magnetic resonance imaging shows emerging prognostic value for predicting outcomes in pulmonary hypertension, coronary artery disease, and myocardial infarction.
AI-CMR perfusion quantification aids CAD risk stratification; extends systematic review evidence for automated prognostic markers.
Background and Objectives: Interest in artificial intelligence (AI) for outcome prediction has grown substantially in recent years. However, the prognostic role of AI using advanced cardiac magnetic resonance imaging (CMR) remains unclear. This systematic review assesses the existing literature on AI in CMR to predict outcomes in patients with cardiovascular disease. Materials and Methods: Medline and Embase were searched for studies published up to November 2021. Any study assessing outcome prediction using AI in CMR in patients with cardiovascular disease was eligible for inclusion. All studies were assessed for compliance with the Checklist for Artificial Intelligence in Medical Imaging (CLAIM). Results: A total of 5 studies were included, with a total of 3679 patients, with 225 deaths and 265 major adverse cardiovascular events. Three methods demonstrated high prognostic accuracy: (1) three-dimensional motion assessment model in pulmonary hypertension (hazard ratio (HR) 2.74, 95%CI 1.73−4.34, p < 0.001), (2) automated perfusion quantification in patients with coronary artery disease (HR 2.14, 95%CI 1.58−2.90, p < 0.001), and (3) automated volumetric, functional, and area assessment in patients with myocardial infarction (HR 0.94, 95%CI 0.92−0.96, p < 0.001). Conclusion: There is emerging evidence of the prognostic role of AI in predicting outcomes for three-dimensional motion assessment in pulmonary hypertension, ischaemia assessment by automated perfusion quantification, and automated functional assessment in myocardial infarction.
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Assadi et al. (2022) conducted a systematic review in Cardiovascular disease (coronary artery disease, myocardial infarction, pulmonary hypertension, and tetralogy of Fallot) (n=3,679). Artificial intelligence in cardiovascular magnetic resonance imaging vs. Standard clinical and imaging parameters was evaluated on Major adverse cardiovascular events (MACE) and death (pooled analysis for automated perfusion quantification in coronary artery disease) (HR 2.02, 95% CI 1.47-2.58, p=<0.001).
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