Allergic diseases are signalling a public health crisis — It is time for a global allergy health plan

Allergic conditions are signalling a public health crisis never seen before.In allergy, the environment is accused as the symptoms are heavily environment-dependent, food, pollen, animals etc.What happens as we evolve from nature -live while using it but unable to tolerate it anymore? INFLAMMATORY RESPONSE WITHOUT A REASONAllergic diseases and asthma indicate distorted immune regulation, which manifests itself by various inflammatory responses at the dermal and mucosal borders between the ecosystem of human body and the wider ecosystems.As a result, patients suffer from various skin, upper and lower airway, and conjunctival symptoms such as itching, swelling, mucus production, sneezing, blocked nose, cough, wheezing, breathlessness, gastrointestinal symptoms, and even lifethreatening anaphylaxis.The immune response misreads the exposure by sensing harmless substances as a threat like proteins released by pollen.Consequently, an inflammatory response is triggered for defence.Clinical symptoms are suppressed by medication, and the severe inflammatory cascade, circulus vitiosus, even cut by biological therapeutics.Allergen-specific immunotherapy (AIT) helps patients to train their immune system not to overreact.The simple and safe sublingual and oral applications have increased the use.