Key result
Symptomatic intracerebral hemorrhage did not occur after cardiac surgery, compared to a 6% incidence among acute cerebrovascular accidents in the general population (0 vs 5 cases; p=0.02).
Why the study?
Does symptomatic intracerebral hemorrhage occur after cardiovascular surgery in the context of routine postoperative anticoagulation?
Cohort (n=5,275)
Yes
Does symptomatic intracerebral hemorrhage occur after cardiovascular surgery in the context of routine postoperative anticoagulation?
Absolute Event Rate: 0% vs 6%
p-value: p=0.02
Symptomatic intracerebral hemorrhage is exceptionally rare after cardiac surgery, suggesting that new postoperative neurological deficits are predominantly ischemic.
Symptomatic ICH appears rare after cardiac surgery; supports ischemic etiology for new deficits but leaves open questions on anticoagulation effects.
BACKGROUND: In the presence of new neurological findings occurring after cardiac surgery, the clinical question is whether to exclude symptomatic intracerebral hemorrhage (ICH), particularly in the context of routine postoperative anticoagulation treatment. METHODS: This is a retrospective 14-year study including 5,275 patients who underwent cardiovascular surgery. The control cohort included all patients with acute cerebrovascular accidents hospitalized in 2 general hospitals in Jerusalem during a 2-month period in 2007 (part of a national survey). RESULTS: After cardiac surgery, 78 patients developed ischemic strokes, mostly of large-vessel etiology. These ischemic strokes occurred more often in patients who underwent combined operations (22/647 = 3.4% vs. 45/3,489 = 1.3%; p = 0.0004). ICH was found in 6% of all acute cerebrovascular accidents in the general survey, but was absent after cardiac surgery (5 vs. 0; p = 0.02). CONCLUSIONS: Despite hypertension as a main risk factor and the administration of postoperative anticoagulation, we found that symptomatic ICH did not occur after cardiac surgery.
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Korn‐Lubetzki et al. (2010) conducted a cohort in Cardiovascular surgery (n=5,275). Cardiac surgery vs. General population with acute cerebrovascular accidents was evaluated on Symptomatic intracerebral hemorrhage (ICH) among acute cerebrovascular accidents (p=0.02). Symptomatic intracerebral hemorrhage did not occur after cardiac surgery, compared to a 6% incidence among acute cerebrovascular accidents in the general population (0 vs 5 cases; p=0.02).
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