Elevated C-Reactive Protein and Hypoalbuminemia Measured before Resection of Colorectal Liver Metastases Predict Postoperative Survival

BACKGROUND: Few studies have investigated whether the Glasgow Prognostic Score (GPS), an inflammation-based prognostic score measured before resection of colorectal liver metastasis (CRLM), can predict postoperative survival. PATIENTS AND METHODS: Sixty-three consecutive patients who underwent curative resection for CRLM were investigated. GPS was calculated on the basis of admission data as follows: patients with both an elevated C-reactive protein (>10 mg/l) and hypoalbuminemia ( or =3 (relative risk 2.83) and GPS1/2 (relative risk 3.07). CONCLUSIONS: GPS measured before operation and the number of liver metastases may be used as novel predictors of postoperative outcomes in patients who underwent curative resection for CRLM.