Key result
Alcoholism (P=0.006), prior depressive symptoms (P=0.016), and severe neurological deficits on admission (P=0.043) were independently associated with post-stroke depression in young adults.
Cohort (n=196)
Post-stroke depression affects over a quarter of young adults with cerebral infarction at long-term follow-up, though it tends to be mild, with alcoholism, prior depression, and initial stroke severity as key risk factors.
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May warrant closer monitoring in young stroke survivors with these risks; extends associations but leaves causal and interventional effects open.
Næss et al. (2005) conducted a cohort in first-ever cerebral infarction (n=196). Alcoholism, prior depressive symptoms, and severe neurological deficits vs. Absence of these risk factors was evaluated on Post-stroke depression (MADRS >= 7). Alcoholism (P=0.006), prior depressive symptoms (P=0.016), and severe neurological deficits on admission (P=0.043) were independently associated with post-stroke depression in young adults.
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