Key result
Higher trait anger score linked to ~21% higher odds of early-onset IHD per unit.
Why the study?
Does trait anger increase the risk of early-onset ischemic heart disease in Pakistani women aged 35 to 55 years?
Case-Control (n=213)
Does trait anger increase the risk of early-onset ischemic heart disease in Pakistani women aged 35 to 55 years?
Trait anger is a significant, potentially modifiable psychosocial risk factor for early-onset ischemic heart disease in Pakistani women.
Trait anger associated with higher early IHD odds in Pakistani women; hypothesis-generating and should not yet change practice.
Empirical research documents that in some cases psychosocial factors conquer greater if not equal risk of IHD. This study was conducted to infer the psychosocial factors associated with the risk of IHD in women. Case control study design was utilized to explore the association of psychosocial factors with the risk of IHD in women aged 35 to 55 years. A sample of 71 women cases diagnosed with IHD and 142 age and gender matched community controls were recruited for this purpose. Binary logistic regression analyses was conducted to ascertain the association of proposed psychosocial factors with the risk of IHD. The values of the coefficients revealed that a unit increase in score of trait anger is associated with increase in the odds of IHD by a factor of 1.21 (95 % CI 1.04 and 1.42). A unit increase in optimism score is associated with decrease in the odds of IHD by a factor of 0.67 (95% CI 0.53 and 0.83). The values of the coefficients reveal that each unit increase in score of social support is associated with decrease in odds of IHD by a factor of 0.91 (95% CI 0.89 and 0.95). The study highlights that women aged 35 to 55 years are protected against the risk of IHD, and trait anger is the only risk factor of IHD. Furthermore trait anger is modifiable and can lay directions for designing preventive cardiac interventions.
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Rafique et al. (2012) conducted a case-control in Ischemic Heart Disease (n=213). Trait anger vs. Lower trait anger scores (matched community controls) was evaluated on Ischemic Heart Disease (OR 1.21, 95% CI 1.04-1.42, p=<0.05). Each unit increase in trait anger score was associated with a 21% increase in the odds of early-onset ischemic heart disease (OR 1.21) among Pakistani women.
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