Key result
A decrease in plasma aldosterone concentration >13.2 pg/mL after direct current cardioversion predicted sinus rhythm maintenance at 30 days with 87% sensitivity and 64% specificity.
Why the study?
Does a decrease in serum aldosterone concentration after successful cardioversion predict maintenance of sinus rhythm in patients with persistent atrial fibrillation?
Observational (n=45)
No
Does a decrease in serum aldosterone concentration after successful cardioversion predict maintenance of sinus rhythm in patients with persistent atrial fibrillation?
A significant decrease in serum aldosterone levels 24 hours after successful cardioversion is predictive of maintaining sinus rhythm at 30 days in patients with persistent atrial fibrillation.
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May identify lower-risk patients for early AF recurrence after cardioversion; hypothesis-generating and requires prospective validation before clinical use.
Wożakowska−Kapłon et al. (2010) conducted an observational in Nonvalvular persistent atrial fibrillation (n=45). Decrease in serum aldosterone concentration vs. No decrease or smaller decrease in serum aldosterone concentration was evaluated on Sinus rhythm maintenance at 30 days. A decrease in plasma aldosterone concentration >13.2 pg/mL after direct current cardioversion predicted sinus rhythm maintenance at 30 days with 87% sensitivity and 64% specificity.
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