Key result
Intense exercise initiates cellular events that can lead to electrical instability and arrhythmias in individuals with underlying conditions such as long QT, Brugada, and Wolff-Parkinson-White syndromes.
Population
Athletes and individuals with inherited arrhythmia syndromes or heritable cardiomyopathies
Design
Review
Authors
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Athletes with channelopathies merit pre-exercise risk assessment; supports mechanistic understanding but leaves prospective trials open.
This review highlights the cellular mechanisms by which intense exercise triggers arrhythmias in athletes with inherited arrhythmogenic conditions.
Stoebner et al. (2012) conducted a review in Arrhythmias associated with long QT, Brugada, Wolff-Parkinson-White syndromes, CPVT, and heritable cardiomyopathies. Intense exercise was evaluated. Intense exercise initiates cellular events that can lead to electrical instability and arrhythmias in individuals with underlying conditions such as long QT, Brugada, and Wolff-Parkinson-White syndromes.
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