Key result
Cardio-STIC established reference ranges for fetal right and left ventricular myocardial wall areas, increasing from 0.86 and 0.82 cm2 at 20 weeks to 2.75 and 2.49 cm2 at 33 weeks of gestation.
Why the study?
Can three-dimensional ultrasound using spatiotemporal image correlation (STIC) establish a reliable reference range for fetal myocardial wall area?
Cross-Sectional (n=371)
Can three-dimensional ultrasound using spatiotemporal image correlation (STIC) establish a reliable reference range for fetal myocardial wall area?
This study establishes a reference range for fetal right and left ventricular myocardial wall area using 3D ultrasound STIC, demonstrating good reproducibility.
Answers are grounded in this paper and cite their sources.
Provides preliminary STIC reference ranges for fetal ventricular assessment; leaves open prospective validation before clinical adoption.
OBJECTIVE: To establish the reference range of the myocardial wall area in the fetus using three-dimensional ultrasound in the rendering mode. METHODS: A prospective, cross-sectional study including 371 singleton, uncomplicated pregnancies at 20 weeks 0 day to 33 weeks 6 days of gestation was carried out. Cardiac volumes were obtained using spatiotemporal image correlation (STIC) at the level of the four-chamber view. The end-diastolic myocardial area of the both ventricles was measured manually. The intraclass correlation coefficient (ICC) was used to assess intra- and interobserver concordance. RESULTS: The mean myocardial area of the fetal right ventricular (RV) wall ranged from 0.86 ± 0.23 cm(2) at 20 weeks 0 day to 2.75 ± 0.69 cm(2) at 33 weeks 6 days of gestation. The mean myocardial area of the fetal left ventricular (LV) wall ranged from 0.82 ± 0.20 cm(2) at 20 weeks 0 day to 2.49 ± 0.59 cm(2) at 33 weeks 6 days of gestation. In addition, intra- and interobserver concordance for the myocardial area of the RV and LV walls was good, with ICC values of 0.94, 0.95, 0.85, and 0.93, respectively. CONCLUSIONS: The reference range for the myocardial area of the RV and LV walls was determined by cardio-STIC in the rendering mode at 20 weeks 0 day to 33 weeks 6 days of gestation, with good concordance between values.
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Barros et al. (2014) conducted a cross-sectional in singleton, uncomplicated pregnancies (n=371). Spatiotemporal image correlation (STIC) in the rendering mode was evaluated on Fetal myocardial wall area reference range. Cardio-STIC established reference ranges for fetal right and left ventricular myocardial wall areas, increasing from 0.86 and 0.82 cm2 at 20 weeks to 2.75 and 2.49 cm2 at 33 weeks of gestation.
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